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| Voxel Based Morphometry techniques allow, for example, to measure volume, thickness and other structural parameters both for cortical and subcortical brain regions | ||||
| Some of these parameters are considered as “structural markers”, which are being identified as of great importance in certain diseases. Thus, it is necessary to have the most accurate techniques. In this service, 116 gray matter structures, both cortical and subcortical, are studied. From these structures, a number of parameters are measured: thickness, volume, density and fractal dimension. Overall, for a given subject, almost 600 gray matter parameters are computed. To this end, the best up-to-date algorithms for structure quantification have been developed and used in this service. These algorithms significantly improve quality, accuracy and speed with respect to previous techniques. Thanks to our database of over 2100 subjects, we can establish whether the values for an individual falls within the normal range or, conversely, represent a decrease compared to the healthy population, in which case it could be an indicator of some pathology. The result of the service is a report with the numerical results of different brain regions, with emphasis on those structures that have greater atrophy in relation to the population. In connection with the NASK knowledge management system, we infer the functionality of atrophied structures, thereby determining possible cognitive or executive impairment. |
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